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Genetics of Hypercoagulable and Hypocoagulable States.
Singh D, Natarajan A, Nand S, Mai HP. Singh D, et al. Neurosurg Clin N Am. 2018 Oct;29(4):493-501. doi: 10.1016/j.nec.2018.06.002. Neurosurg Clin N Am. 2018. PMID: 30223962 Review.
Virchow triad includes venous stasis, hypercoagulability, and vascular injury. Natural anticoagulants include protein C, protein S, and antithrombin. Factor V Leiden is the most common inherited thrombophilia, followed by prothrombin gene mutation. ... …
Virchow triad includes venous stasis, hypercoagulability, and vascular injury. Natural anticoagulants include protein C, pr …
Protein C deficiency as the major cause of thrombophilias in childhood.
Ohga S, Ishiguro A, Takahashi Y, Shima M, Taki M, Kaneko M, Fukushima K, Kang D, Hara T; Japan Childhood Thrombophilia Study Group. Ohga S, et al. Pediatr Int. 2013 Jun;55(3):267-71. doi: 10.1111/ped.12102. Pediatr Int. 2013. PMID: 23521084 Review.
Factor V Leiden (G1691A) and factor II mutation (G20210A) are the leading causes of inherited thrombophilias in Caucasians, but are not found in Asian ancestries. Protein S (PS), protein C (PC) and antithrombin (AT) activity are reportedly low in 65% of adult …
Factor V Leiden (G1691A) and factor II mutation (G20210A) are the leading causes of inherited thrombophilias in Caucasians, but are not foun …
Plasma-derived human factor X concentrate for the treatment of patients with hereditary factor X deficiency.
Escobar MA, Kavakli K. Escobar MA, et al. Haemophilia. 2024 Jan;30(1):59-67. doi: 10.1111/hae.14894. Epub 2023 Oct 30. Haemophilia. 2024. PMID: 37902395 Review.
INTRODUCTION: Hereditary factor X (FX) deficiency (HFXD) is an autosomal recessive rare bleeding disorder that leads to defects in the FX protein. ...METHODS: Five studies that examined the use of pdFX in patients with mild (plasma FX activity [FX:C …
INTRODUCTION: Hereditary factor X (FX) deficiency (HFXD) is an autosomal recessive rare bleeding disorder that leads to …