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Cancer Predisposition Syndromes in Neuro-oncology.
Na B, Shah S, Nghiemphu PL. Na B, et al. Semin Neurol. 2024 Feb;44(1):16-25. doi: 10.1055/s-0043-1777702. Epub 2023 Dec 14. Semin Neurol. 2024. PMID: 38096910 Review.
Autophagy and ethanol neurotoxicity.
Luo J. Luo J. Autophagy. 2014;10(12):2099-108. doi: 10.4161/15548627.2014.981916. Autophagy. 2014. PMID: 25484085 Free PMC article. Review.
Nervous system (NS) Tumors in Cancer Predisposition Syndromes.
Patil P, Pencheva BB, Patil VM, Fangusaro J. Patil P, et al. Neurotherapeutics. 2022 Oct;19(6):1752-1771. doi: 10.1007/s13311-022-01277-w. Epub 2022 Sep 2. Neurotherapeutics. 2022. PMID: 36056180 Free PMC article. Review.
Minireview: Lymphangioleiomyomatosis (LAM): The "Other" Steroid-Sensitive Cancer.
Prizant H, Hammes SR. Prizant H, et al. Endocrinology. 2016 Sep;157(9):3374-83. doi: 10.1210/en.2016-1395. Epub 2016 Jul 13. Endocrinology. 2016. PMID: 27409646 Free PMC article. Review.
LAM cells contain inactivating mutations in genes encoding tuberous sclerosis 1 or 2, proteins that normally limit cell growth through suppression of mammalian target of rapamycin complex 1. ...
LAM cells contain inactivating mutations in genes encoding tuberous sclerosis 1 or 2, proteins that normally limit cell …
Taking aim at Alzheimer's disease through the mammalian target of rapamycin.
Maiese K. Maiese K. Ann Med. 2014 Dec;46(8):587-96. doi: 10.3109/07853890.2014.941921. Epub 2014 Aug 8. Ann Med. 2014. PMID: 25105207 Free PMC article. Review.
The mammalian target of rapamycin (mTOR) and its protein complexes mTOR Complex 1 (mTORC1) and mTOR Complex 2 (mTORC2) offer exciting and unique avenues of intervention for AD through the oversight of programmed cell death pathways of apoptosis, autophagy, and necroptosis. mTOR m …
The mammalian target of rapamycin (mTOR) and its protein complexes mTOR Complex 1 (mTORC1) and mTOR Complex 2 (mTORC2) offer exciting and un …
Molecular uropathology and cancer genetics for the urologist: key findings for classification and diagnosis.
Compérat E, Oszwald A, Wasinger G, Kläger J, Hassler MR, Shariat SF. Compérat E, et al. Curr Opin Urol. 2022 Sep 1;32(5):451-455. doi: 10.1097/MOU.0000000000001025. Epub 2022 Jul 18. Curr Opin Urol. 2022. PMID: 35916009 Review.
In the development of RCC, different genetic pathways such as Von Hippel-Lindau, but also tuberous sclerosis 1/2 and others play a major role in tumor development. ...
In the development of RCC, different genetic pathways such as Von Hippel-Lindau, but also tuberous sclerosis 1/2 and ot …
Treatment of Advanced Malignant Uterine Perivascular Epithelioid Cell Tumor with mTOR Inhibitors: Single-institution Experience and Review of the Literature.
Starbuck KD, Drake RD, Budd GT, Rose PG. Starbuck KD, et al. Anticancer Res. 2016 Nov;36(11):6161-6164. doi: 10.21873/anticanres.11208. Anticancer Res. 2016. PMID: 27793946 Review.
Many have malignant behavior, and no successful treatment strategy has been established. Identification of mutations in the tuberous sclerosis 1 (TSC1) and TSC2 genes producing constitutive activation of the mammalian target of rapamycin (mTOR) pathway presen …
Many have malignant behavior, and no successful treatment strategy has been established. Identification of mutations in the tuberous …