Vaginal estrogen for genitourinary syndrome of menopause: a systematic review.
Rahn DD, Carberry C, Sanses TV, Mamik MM, Ward RM, Meriwether KV, Olivera CK, Abed H, Balk EM, Murphy M; Society of Gynecologic Surgeons Systematic Review Group.
Rahn DD, et al.
Obstet Gynecol. 2014 Dec;124(6):1147-1156. doi: 10.1097/AOG.0000000000000526.
Obstet Gynecol. 2014.
PMID: 25415166
Free PMC article.
Review.
Compared with placebo, vaginal estrogens improved dryness, dyspareunia, urinary urgency, frequency, and stress urinary incontinence (SUI) and urgency urinary incontinence (UUI). ...Endometrial hyperplasia and adenocarcinoma were extremely rare among those receiving vagi …
Compared with placebo, vaginal estrogens improved dryness, dyspareunia, urinary urgency, frequency, and stress urinary incontinence ( …