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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 2
1968 1
1969 3
1970 1
1972 1
1973 5
1974 4
1975 2
1976 6
1977 4
1978 1
1979 5
1980 9
1981 3
1982 1
1983 2
1984 8
1985 9
1986 12
1987 24
1988 40
1989 39
1990 55
1991 30
1992 47
1993 44
1994 57
1995 42
1996 36
1997 31
1998 50
1999 53
2000 56
2001 101
2002 114
2003 82
2004 87
2005 79
2006 88
2007 78
2008 68
2009 63
2010 93
2011 98
2012 119
2013 141
2014 155
2015 171
2016 212
2017 191
2018 168
2019 150
2020 232
2021 252
2022 251
2023 224
2024 88

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3,624 results

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Page 1
West syndrome: a comprehensive review.
Pavone P, Polizzi A, Marino SD, Corsello G, Falsaperla R, Marino S, Ruggieri M. Pavone P, et al. Neurol Sci. 2020 Dec;41(12):3547-3562. doi: 10.1007/s10072-020-04600-5. Epub 2020 Aug 22. Neurol Sci. 2020. PMID: 32827285 Free PMC article. Review.
Since its first clinical description (on his son) by William James West (1793-1848) in 1841, and the definition of the classical triad of (1) infantile spasms; (2) hypsarrhythmia, and (3) developmental arrest or regression as "West syndrome", ne …
Since its first clinical description (on his son) by William James West (1793-1848) in 1841, and the definition of the classical tria …
Dravet syndrome.
Lagae L. Lagae L. Curr Opin Neurol. 2021 Apr 1;34(2):213-218. doi: 10.1097/WCO.0000000000000902. Curr Opin Neurol. 2021. PMID: 33395108 Review.
PURPOSE OF REVIEW: This review will illustrate the electroclinical description of Dravet syndrome, highlighting the difficulty to understand the correlation between the SCN1A mutation and clinical characteristics, including the frequent comorbidities. ...Genetic treatments …
PURPOSE OF REVIEW: This review will illustrate the electroclinical description of Dravet syndrome, highlighting the difficulty to und …
Current and future pharmacotherapy options for drug-resistant epilepsy.
Elkommos S, Mula M. Elkommos S, et al. Expert Opin Pharmacother. 2022 Dec;23(18):2023-2034. doi: 10.1080/14656566.2022.2128670. Epub 2022 Sep 27. Expert Opin Pharmacother. 2022. PMID: 36154780 Review.
EXPERT OPINION: Current pharmacotherapy options for drug-resistant epilepsy include perampanel, brivaracetam and the newly approved cenobamate for focal epilepsies; cannabidiol (Epidiolex) for Lennox-Gastaut Syndrome (LGS), Dravet and Tuberous Sclerosis Complex (TSC); fenf …
EXPERT OPINION: Current pharmacotherapy options for drug-resistant epilepsy include perampanel, brivaracetam and the newly approved cenobama …
Cannabis for the Treatment of Epilepsy: an Update.
Gaston TE, Szaflarski JP. Gaston TE, et al. Curr Neurol Neurosci Rep. 2018 Sep 8;18(11):73. doi: 10.1007/s11910-018-0882-y. Curr Neurol Neurosci Rep. 2018. PMID: 30194563 Review.
The RCTs have shown significant seizure reduction compared to placebo in patients with Dravet syndrome and Lennox-Gastaut syndrome. Finally, we describe the available data on adverse effects and drug-drug interactions with highly purified CBD. ...
The RCTs have shown significant seizure reduction compared to placebo in patients with Dravet syndrome and Lennox-Gastaut syndrome
Infantile Spasms: Outcome in Clinical Studies.
Riikonen R. Riikonen R. Pediatr Neurol. 2020 Jul;108:54-64. doi: 10.1016/j.pediatrneurol.2020.01.015. Epub 2020 Feb 4. Pediatr Neurol. 2020. PMID: 32305143 Review.
Children with infantile spasms are likely to have a poor outcome. Outcome measures for infantile spasms include primary response to treatment, relapse of spasms, neurological development, death, and progression to another type of epilepsy (Conse …
Children with infantile spasms are likely to have a poor outcome. Outcome measures for infantile spasms include …
CDKL5 Deficiency Disorder-Related Epilepsy: A Review of Current and Emerging Treatment.
Hong W, Haviland I, Pestana-Knight E, Weisenberg JL, Demarest S, Marsh ED, Olson HE. Hong W, et al. CNS Drugs. 2022 Jun;36(6):591-604. doi: 10.1007/s40263-022-00921-5. Epub 2022 May 28. CNS Drugs. 2022. PMID: 35633486 Free PMC article. Review.
Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is a developmental and epileptic encephalopathy with infantile-onset epilepsy. Most individuals with CDD develop refractory epilepsy with multiple seizure types. Management of seizures in CDD remains challeng …
Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is a developmental and epileptic encephalopathy with infantile-onset …
West Syndrome: A Review and Guide for Paediatricians.
D'Alonzo R, Rigante D, Mencaroni E, Esposito S. D'Alonzo R, et al. Clin Drug Investig. 2018 Feb;38(2):113-124. doi: 10.1007/s40261-017-0595-z. Clin Drug Investig. 2018. PMID: 29086890 Review.
West syndrome (WS), also known as infantile spasms, occurs in infancy with a peak between 4 and 7 months. Spasms, neurodevelopmental regression and hypsarrhythmia on electroencephalogram (EEG) basically define WS. ...
West syndrome (WS), also known as infantile spasms, occurs in infancy with a peak between 4 and 7 months. Spa
Cannabidiol Interactions with Medications, Illicit Substances, and Alcohol: a Comprehensive Review.
Balachandran P, Elsohly M, Hill KP. Balachandran P, et al. J Gen Intern Med. 2021 Jul;36(7):2074-2084. doi: 10.1007/s11606-020-06504-8. Epub 2021 Jan 29. J Gen Intern Med. 2021. PMID: 33515191 Free PMC article. Review.
In 2018, a CBD-based oral solution, Epidiolex, was approved by the FDA to treat two severe forms of pediatric epilepsy, Dravet syndrome, and Lennox-Gastaut syndrome. Although only these two syndromes are recognized indications for CBD, it has been consumed in an unr …
In 2018, a CBD-based oral solution, Epidiolex, was approved by the FDA to treat two severe forms of pediatric epilepsy, Dravet syndrome
Summary of recommendations for the management of infantile seizures: Task Force Report for the ILAE Commission of Pediatrics.
Wilmshurst JM, Gaillard WD, Vinayan KP, Tsuchida TN, Plouin P, Van Bogaert P, Carrizosa J, Elia M, Craiu D, Jovic NJ, Nordli D, Hirtz D, Wong V, Glauser T, Mizrahi EM, Cross JH. Wilmshurst JM, et al. Epilepsia. 2015 Aug;56(8):1185-97. doi: 10.1111/epi.13057. Epub 2015 Jun 30. Epilepsia. 2015. PMID: 26122601 Free article. Review.
Standard care should permit genetic counseling by trained personal at all levels of care (expert opinion). Genetic evaluation for Dravet syndrome, and other infantile-onset epileptic encephalopathies, should be available in tertiary care (weak evidence, level C reco …
Standard care should permit genetic counseling by trained personal at all levels of care (expert opinion). Genetic evaluation for Dravet …
3,624 results