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Study Reveals a Cell-Eat-Cell World
From normal vertebrate development to tumor cell cannibalism, cell-in-cell events occur in many different contexts across the tree of life
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Research findings and data from the National Library of Medicine
PubMed articles
A nonapoptotic cell death process, entosis, that occurs by cell-in-cell invasion
Epithelial cells require attachment to extracellular matrix (ECM) to suppress an apoptotic cell death program termed anoikis. Here we describe a nonapoptotic cell death p …
Cell-in-cell phenomena across the tree of life
Cells in obligately multicellular organisms by definition have aligned fitness interests, minimum conflict, and cannot reproduce independently. However, some cells eat ot …
Entosis Controls a Developmental Cell Clearance in C. elegans
Metazoan cell death mechanisms are diverse and include numerous non-apoptotic programs. One program called entosis involves the invasion of live cells into their neighbor …
Entosis allows timely elimination of the luminal epithelial barrier for embryo implantation
During implantation, uterine luminal epithelial (LE) cells first interact with the blastocyst trophectoderm. Within 30 hr after the initiation of attachment, LE cells sur …
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