Ssl1 mutant for a subunit of TFIIH response to methyl methanesulfonate
Summary:
Analysis of Ssl1 mutant for a subunit of TFIIH treated with methyl methanesulfonate (MMS). Ssl1 mutant contains C406A substitution and is sensitive to DNA damaging agents such as MMS. Results provide insight into the relationship between transcription and DNA repair.
Takagi Y, Masuda CA, Chang WH, Komori H et al. Ubiquitin ligase activity of TFIIH and the transcriptional response to DNA damage. Mol Cell 2005 Apr 15;18(2):237-43. PMID: 15837426