Analysis of liver of 74 day old Sprague-Dawley males fed a vitamin A (retinol) deficient diet for 53 days. The liver is the major storage organ for vitamin A, is involved in vitamin A homeostasis, and expresses retinoic acid-regulated transcription factors.
McClintick JN, Crabb DW, Tian H, Pinaire J et al. Global effects of vitamin A deficiency on gene expression in rat liver: evidence for hypoandrogenism. J Nutr Biochem 2006 May;17(5):345-55. PMID: 16214324
