Telomerase reverse transcriptase overexpression effect on CD4+ lymphocytes
Summary:
Analysis of CD4+ T cells overexpressing green fluorescent protein telomerase reverse transcriptase fusion protein (GFP-hTERT). hTERT encodes catalytic reverse transcriptase subunit of telomerase. Provides insight into long-term consequences of hTERT overexpression in T lymphocytes.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Röth A, Baerlocher GM, Schertzer M, Chavez E et al. Telomere loss, senescence, and genetic instability in CD4+ T lymphocytes overexpressing hTERT. Blood 2005 Jul 1;106(1):43-50. PMID: 15741219
