Glucocorticoid effect on lens epithelial cells: time course
Summary:
Analysis of cultured immortalized lens epithelial cells (LEC) 4 and 16 hours after treatment with 1 uM dexamethasone, a glucocorticoid steroid hormone. Long-term glucocorticoid use can induce cataract formation. Results identify glucocorticoid targets and short-term effects of glucocorticoid on LECs
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Gupta V, Galante A, Soteropoulos P, Guo S et al. Global gene profiling reveals novel glucocorticoid induced changes in gene expression of human lens epithelial cells. Mol Vis 2005 Nov 23;11:1018-40. PMID: 16319822
