DataSet Record GDS1361: Expression Profiles Data Analysis Tools Sample Subsets
Title: Testosterone effect on meibomian gland
Cluster AnalysisGDS1361 Cluster Image
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Summary: Analysis of meibomian glands from orchiectomized BALB/c adults treated with testosterone for 14 days. Androgen deficiency associated with glandular dysfunction and evaporative dry eye. Lacrimal and submandibular glands included. Results suggest pathways regulated by androgens in meibomian glands.
Organism: Mus musculus
Platform: GPL1310: Amersham CodeLink UniSet Mouse I Bioarray
Citations:
  • Schirra F, Suzuki T, Richards SM, Jensen RV et al. Androgen control of gene expression in the mouse meibomian gland. Invest Ophthalmol Vis Sci 2005 Oct;46(10):3666-75. PMID: 16186348
  • Suzuki T, Schirra F, Richards SM, Treister NS et al. Estrogen's and progesterone's impact on gene expression in the mouse lacrimal gland. Invest Ophthalmol Vis Sci 2006 Jan;47(1):158-68. PMID: 16384958
  • Treister NS, Richards SM, Suzuki T, Jensen RV et al. Influence of androgens on gene expression in the BALB/c mouse submandibular gland. J Dent Res 2005 Dec;84(12):1187-92. PMID: 16304452
  • Tsai PS, Evans JE, Green KM, Sullivan RM et al. Proteomic analysis of human meibomian gland secretions. Br J Ophthalmol 2006 Mar;90(3):372-7. PMID: 16488965
Reference Series: GSE1582 Sample count: 18
Value type: transformed count Series published: 2004/11/24