Analysis of atrium from patients with permanent atrial fibrillation (AF). AF is associated with extensive structural, contractile, and electrophysiological remodeling. Results identify adoption of a ventricular-like genomic signature as a general feature of the fibrillating atrium.
GPL97:
[HG-U133B] Affymetrix Human Genome U133B Array
Citations:
Barth AS, Merk S, Arnoldi E, Zwermann L et al. Functional profiling of human atrial and ventricular gene expression. Pflugers Arch 2005 Jul;450(4):201-8. PMID: 15877233
Barth AS, Merk S, Arnoldi E, Zwermann L et al. Reprogramming of the human atrial transcriptome in permanent atrial fibrillation: expression of a ventricular-like genomic signature. Circ Res 2005 May 13;96(9):1022-9. PMID: 15817885
