DataSet Record GDS1596: Expression Profiles Data Analysis Tools Sample Subsets
Title: p38 inhibitor PD169316 effect on embryonic stem derived differentiated cells (U74 Version 2)
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Summary: Analysis of embryonic stem cells differentiated in the presence of PD169316, an inhibitor of p38 that blocks apoptosis without altering differentiation. Results identify gene families whose transcriptional regulation correlates with cell fate: differentiation with or without apoptosis.
Organism: Mus musculus
Platform: GPL81: [MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citations:
  • Duval D, Trouillas M, Thibault C, Dembelé D et al. Apoptosis and differentiation commitment: novel insights revealed by gene profiling studies in mouse embryonic stem cells. Cell Death Differ 2006 Apr;13(4):564-75. PMID: 16311515
  • Trouillas M, Saucourt C, Duval D, Gauthereau X et al. Bcl2, a transcriptional target of p38alpha, is critical for neuronal commitment of mouse embryonic stem cells. Cell Death Differ 2008 Sep;15(9):1450-9. PMID: 18437159
Reference Series: GSE2042 Sample count: 4
Value type: count Series published: 2005/12/21