Sleep deprivation effect on the brain: time course
Summary:
Analysis of brain of Canton-S females deprived of sleep by perturbations during their normal sleep period. Perturbation effect also assessed during their active period to control for its effect during sleep deprivation. Results suggest processes altered during prolonged wakefulness and during sleep.
Zimmerman JE, Rizzo W, Shockley KR, Raizen DM et al. Multiple mechanisms limit the duration of wakefulness in Drosophila brain. Physiol Genomics 2006 Nov 27;27(3):337-50. PMID: 16954408