Analysis of Ewing family tumor (EFT) and neuroblastoma (NB) samples. Distinguishing EFTs from other small round blue cell tumors (SRBCTs), such as NBs, by histologic methods is often difficult. Results identify EF-associated genes that enable molecular discrimination between EFTs and other SRBCTs.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citations:
Staege MS, Hutter C, Neumann I, Foja S et al. DNA microarrays reveal relationship of Ewing family tumors to both endothelial and fetal neural crest-derived cells and define novel targets. Cancer Res 2004 Nov 15;64(22):8213-21. PMID: 15548687
Burdach S, Plehm S, Unland R, Dirksen U et al. Epigenetic maintenance of stemness and malignancy in peripheral neuroectodermal tumors by EZH2. Cell Cycle 2009 Jul 1;8(13):1991-6. PMID: 19502792
Staege MS. Gene Expression Music Algorithm-Based Characterization of the Ewing Sarcoma Stem Cell Signature. Stem Cells Int 2016;2016:7674824. PMID: 27446218
Staege MS. A short treatise concerning a musical approach for the interpretation of gene expression data. Sci Rep 2015 Oct 16;5:15281. PMID: 26472273