Zucker diabetic fatty model of type 2 diabetes: various insulin-sensitive tissues
Summary:
Analysis of adipose, skeletal muscle, and liver tissues of Zucker diabetic fatty animals at pre-diabetic and diabetic stages. ZDF animals have a mutated leptin receptor. Results provide insight into the molecular mechanisms responsible for insulin resistance and progression to type 2 diabetes.
Suh YH, Kim Y, Bang JH, Choi KS et al. Analysis of gene expression profiles in insulin-sensitive tissues from pre-diabetic and diabetic Zucker diabetic fatty rats. J Mol Endocrinol 2005 Apr;34(2):299-315. PMID: 15821098
