Mono-(2-ethylhexyl) phthalate effect on prepubertal testes: time course
Summary:
Analysis of testes of postnatal day 28 animals at various time points up to 12 hrs after acute exposure to mono-(2-ethylhexyl) phthalate. Phthalate plasticizers can damage fetal and prepubertal testis. Results provide insight into mechanisms of prepubertal phthalate-induced testicular injury.
GPL1355:
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Citation:
Lahousse SA, Wallace DG, Liu D, Gaido KW et al. Testicular gene expression profiling following prepubertal rat mono-(2-ethylhexyl) phthalate exposure suggests a common initial genetic response at fetal and prepubertal ages. Toxicol Sci 2006 Oct;93(2):369-81. PMID: 16809437