Classical fear conditioning effect on amygdala and hippocampus
Summary:
Comparison of amygdalae and hippocampi of animals subjected to classical fear conditioning (CFC), which consists of a 3-minute exposure to the conditioning chamber, a 30-second exposure to tone, and a 2-second, 1.5-mA footshock. CFC induced greater gene expression changes in the amygdala.
GPL81:
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citation:
Keeley MB, Wood MA, Isiegas C, Stein J et al. Differential transcriptional response to nonassociative and associative components of classical fear conditioning in the amygdala and hippocampus. Learn Mem 2006 Mar-Apr;13(2):135-42. PMID: 16547164
