Glioma-derived stem cell factor effect on angiogenesis in the brain
Summary:
Analysis of gliomas of different grades. Stem cell factor (SCF) is overexpressed by glioma cells but its role in gliomagenesis has been unclear. Results identify a positive correlation of SCF expression with increasing glioma grade which supports a role for SCF in tumor angiogenesis in the brain.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Sun L, Hui AM, Su Q, Vortmeyer A et al. Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain. Cancer Cell 2006 Apr;9(4):287-300. PMID: 16616334
