Flagellin effect on toll-like receptor 5 deficient intestinal epithelial cells
Summary:
Analysis of intestinal epithelial cells (IECs) from toll-like receptor 5 (TLR5) null animals stimulated with flagellin. TLR5 mediates the immune response to flagellin. Results provide insight into the role of IECs in the innate immune response mediated by TLR5.
Uematsu S, Jang MH, Chevrier N, Guo Z et al. Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells. Nat Immunol 2006 Aug;7(8):868-74. PMID: 16829963
