Septic neutrophil response to lipopolysaccharide and high mobility group box 1 protein
Summary:
Analysis of septic neutrophils treated with lipopolysaccharide or high mobility group box 1 (HMGB1) protein. Neutrophils isolated from patients with sepsis-induced acute lung injury (ALI). HMGB1 is a late mediator of endotoxin lethality, and neutrophils play a role in endotoxemia-associated ALI.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Silva E, Arcaroli J, He Q, Svetkauskaite D et al. HMGB1 and LPS induce distinct patterns of gene expression and activation in neutrophils from patients with sepsis-induced acute lung injury. Intensive Care Med 2007 Oct;33(10):1829-39. PMID: 17581740
