Low concentrations of 17beta-estradiol effect on breast cancer cell line
Summary:
Analysis of breast cancer MCF7/BUS cells treated with 17beta-estradiol (E2) at concentrations up to 100 pM. Results compared to that from an experiment examining the response to hormone starvation (GDS2323). Results provide insight into the E2 sensitivity of E2 inducible or suppressible genes.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Coser KR, Chesnes J, Hur J, Ray S et al. Global analysis of ligand sensitivity of estrogen inducible and suppressible genes in MCF7/BUS breast cancer cells by DNA microarray. Proc Natl Acad Sci U S A 2003 Nov 25;100(24):13994-9. PMID: 14610279