Analysis of hearts of animals subjected to chronic cardiac pacing for 3 or 4 weeks. The transition from compensated dysfunction to decompensated heart failure (HF) occurs between the third and fourth week of pacing. Results provide insight into the progression to decompensated HF.
Ojaimi C, Qanud K, Hintze TH, Recchia FA. Altered expression of a limited number of genes contributes to cardiac decompensation during chronic ventricular tachypacing in dogs. Physiol Genomics 2007 Mar 14;29(1):76-83. PMID: 17164392
