Polycomb group protein depletion effect on embryonic fibroblasts
Summary:
Analysis of embryonic fibroblasts depleted of the polycomb group (PcG) proteins EZH2, EED, SUZ12, or BMI-1. PcG proteins form complexes that regulate the expression of homeotic genes during development. Results provide insight into the mechanisms employed by PcGs to control development.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Bracken AP, Dietrich N, Pasini D, Hansen KH et al. Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev 2006 May 1;20(9):1123-36. PMID: 16618801
