Analysis of human umbilical vein endothelial cells treated with nickel chloride. Nickel compounds, important carcinogens and inducers of contact allergy reactions, are activators of endothelial cells. Results provide insight into the signaling pathways mediating the cellular responses to nickel.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Viemann D, Schmidt M, Tenbrock K, Schmid S et al. The contact allergen nickel triggers a unique inflammatory and proangiogenic gene expression pattern via activation of NF-kappaB and hypoxia-inducible factor-1alpha. J Immunol 2007 Mar 1;178(5):3198-207. PMID: 17312168
