Analysis of sorted peripheral blood lymphocytes (CD8 T cells, CD4 T cells, B cells, NK cells) from patients with melanoma. These subpopulations are involved in antitumor responses and negatively impacted by cancer. Results provide insight into molecular mechanisms of immune dysfunction in cancer.
GPL887:
Agilent-012097 Human 1A Microarray (V2) G4110B (Feature Number version)
Citation:
Critchley-Thorne RJ, Yan N, Nacu S, Weber J et al. Down-regulation of the interferon signaling pathway in T lymphocytes from patients with metastatic melanoma. PLoS Med 2007 May;4(5):e176. PMID: 17488182
