LIM-only protein 4 induction effect on breast cancer cell line (HG-U133A)
Summary:
Analysis of breast cancer MCF-7 cells following the induction of expression of nuclear LIM-only protein 4 (LMO4). LMO4 is upregulated in breast cancer. Results provide insight into the role of LMO4 in promoting tumor formation.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Wang N, Lin KK, Lu Z, Lam KS et al. The LIM-only factor LMO4 regulates expression of the BMP7 gene through an HDAC2-dependent mechanism, and controls cell proliferation and apoptosis of mammary epithelial cells. Oncogene 2007 Sep 27;26(44):6431-41. PMID: 17452977