Estrogen-related receptor gamma deficiency effect on the fetal heart
Summary:
Analysis of hearts from fetuses lacking ERRgamma, a gene expressed at high levels in fetal and postnatal heart. Results provide insight into the role of ERRgamma in the heart’s metabolic switch from a dependence on carbohydrates during fetal life to a dependence on postnatal oxidative metabolism.
Alaynick WA, Kondo RP, Xie W, He W et al. ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart. Cell Metab 2007 Jul;6(1):13-24. PMID: 17618853
