LEDGF/p75 transcription factor deficiency effect on T-cell line
Summary:
Analysis of Jurkat T-cells depleted for the LEDGF/p75 transcription factor. LEDGF/p75 is involved in targeting HIV DNA integration. Results provide insight into the mechanisms controlling HIV integration.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Wang GP, Ciuffi A, Leipzig J, Berry CC et al. HIV integration site selection: analysis by massively parallel pyrosequencing reveals association with epigenetic modifications. Genome Res 2007 Aug;17(8):1186-94. PMID: 17545577