Air pollutant and oxidized lipid effect on microvascular endothelial cells: dose response
Summary:
Analysis of microvascular endothelial cells treated at various concentrations of the model air pollutant diesel exhaust particles (DEP), an oxidized phospholipid (ox-PAPC), or both. Results provide insight into the synergistic effect of DEP and ox-PAPC in promoting vascular inflammation.
Gong KW, Zhao W, Li N, Barajas B et al. Air-pollutant chemicals and oxidized lipids exhibit genome-wide synergistic effects on endothelial cells. Genome Biol 2007;8(7):R149. PMID: 17655762
