2,3,7,8-tetrachlorodibenzo-p-dioxin effect on the ovary: dose response (I)
Summary:
Analysis of ovaries following exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) at concentrations of up to 100 parts per billion (ppb). TCDD is a reproductive toxicant and endocrine disruptor in vertebrates. Results provide insight into molecular mechanisms underlying TCDD toxicity.
Heiden TC, Struble CA, Rise ML, Hessner MJ et al. Molecular targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) within the zebrafish ovary: insights into TCDD-induced endocrine disruption and reproductive toxicity. Reprod Toxicol 2008 Jan;25(1):47-57. PMID: 17884332