DataSet Record GDS2931: Expression Profiles Data Analysis Tools Sample Subsets
Title: Rheumatoid arthritis and osteoarthritis: synovial fibroblasts
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Summary: Comparison of synovial fibroblasts from patients with rheumatoid arthritis (RA) to those with osteoarthritis (OA). RA is characterized by chronic inflammation and destruction of multiple joints. OA is a degenerative disease resulting from the breakdown of cartilage.
Organism: Homo sapiens
Platform: GPL8300: [HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array
Citations:
  • Pohlers D, Beyer A, Koczan D, Wilhelm T et al. Constitutive upregulation of the transforming growth factor-beta pathway in rheumatoid arthritis synovial fibroblasts. Arthritis Res Ther 2007;9(3):R59. PMID: 17594488
  • Geurts J, Vermeij EA, Pohlers D, Arntz OJ et al. A novel Saa3-promoter reporter distinguishes inflammatory subtypes in experimental arthritis and human synovial fibroblasts. Ann Rheum Dis 2011 Jul;70(7):1311-9. PMID: 21474483
Reference Series: GSE7669 Sample count: 12
Value type: count Series published: 2007/08/30