Cardiomyocyte response to biomechanical stretch in vitro
Summary:
Analysis of neonatal ventricular cardiomyocytes subjected to both biomechanical stretch stress and pharmacological (i.e., phenylephrine, PE) induction of hypertrophy. Results provide insight into how mechanical stress is sensed and transduced in cardiomyocytes on the molecular level.
GPL1355:
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Citation:
Frank D, Kuhn C, Brors B, Hanselmann C et al. Gene expression pattern in biomechanically stretched cardiomyocytes: evidence for a stretch-specific gene program. Hypertension 2008 Feb;51(2):309-18. PMID: 18158353
