YAP overexpression effect on MCF10A mammary epithelial cell line
Summary:
Analysis of MCF10A mammary epithelial cells overexpressing the transcriptional coactivator YAP. The Hippo pathway impinges on YAP in mammals to coordinate cell proliferation and apoptosis. Results provide insight into molecular components of the Hippo pathway in mammalian cells.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Zhang J, Smolen GA, Haber DA. Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway. Cancer Res 2008 Apr 15;68(8):2789-94. PMID: 18413746
