DataSet Record GDS3223: Expression Profiles Data Analysis Tools Sample Subsets
Title: Interleukin-13 effect on esophageal epithelial cells from eosinophilic esophagitis patients
Cluster AnalysisGDS3223 Cluster Image
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Summary: Analysis of primary esophageal epithelial cells from eosinophilic esophagitis (EE) patients following 100ng/mL interleukin-13 (IL-13) stimulation. The T-helper type 2 cytokine IL-13 plays a pivotal role in eosinophilic inflammation. Results provide insight into the role of IL-13 in EE pathogenesis.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citations:
  • Blanchard C, Mingler MK, Vicario M, Abonia JP et al. IL-13 involvement in eosinophilic esophagitis: transcriptome analysis and reversibility with glucocorticoids. J Allergy Clin Immunol 2007 Dec;120(6):1292-300. PMID: 18073124
  • Blanchard C, Stucke EM, Burwinkel K, Caldwell JM et al. Coordinate interaction between IL-13 and epithelial differentiation cluster genes in eosinophilic esophagitis. J Immunol 2010 Apr 1;184(7):4033-41. PMID: 20208004
Reference Series: GSE8853 Sample count: 6
Value type: count Series published: 2007/12/21