Intestinal tissue xenograft response to pathogen Shigella flexneri infection in vivo
Summary:
Analysis of human intestinal xenotransplants infected with Shigella flexneri (virulent wild-type M90T, virulent mxiE mutant, and avirulent BS176 strains). Virulent S. flexneri are highly contagious enteric pathogens. Results provide insight into the intestinal innate immune response to infection.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Sperandio B, Regnault B, Guo J, Zhang Z et al. Virulent Shigella flexneri subverts the host innate immune response through manipulation of antimicrobial peptide gene expression. J Exp Med 2008 May 12;205(5):1121-32. PMID: 18426984
