Pediatric malignant germ cell tumors: yolk sac tumors and seminomas
Summary:
Analysis of yolk sac tumors (YSTs) and seminomas, the two principal histological variants of pediatric malignant germ cell tumors (MGCTs). Seminomas and YSTs are presumed to arise from the same progenitor cell. Results provide insight into the molecular basis for the divergence of pediatric MGCTs.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Palmer RD, Barbosa-Morais NL, Gooding EL, Muralidhar B et al. Pediatric malignant germ cell tumors show characteristic transcriptome profiles. Cancer Res 2008 Jun 1;68(11):4239-47. PMID: 18519683
