Cyclooxygenase-2 inhibitor celecoxib effect on colorectal adenocarcinoma
Summary:
Analysis of colorectal adenocarcinomas resected from patients treated with celecoxib for 7 days. Celecoxib is a cycooxygenase-2 inibitor that exhibits anti-cancer activity. Results provide insight into the mechanism of action of celecoxib in vivo.
GPL8300:
[HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array
Citation:
Auman JT, Church R, Lee SY, Watson MA et al. Celecoxib pre-treatment in human colorectal adenocarcinoma patients is associated with gene expression alterations suggestive of diminished cellular proliferation. Eur J Cancer 2008 Aug;44(12):1754-60. PMID: 18653328
