Analysis of kidneys from lean and obese animals fed a diet supplemented with rosiglitazone for 12 weeks. Rosiglitazone is a thiazolidinedione drug used to treat diabetes. Results provide insight into the mechanism of action of rosiglitazone.
GPL1355:
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Citation:
Song J, Liu H, Ressom HW, Tiwari S et al. Chronic rosiglitazone therapy normalizes expression of ACE1, SCD1 and other genes in the kidney of obese Zucker rats as determined by microarray analysis. Exp Clin Endocrinol Diabetes 2008 Jun;116(6):315-25. PMID: 18700276
