Analysis of kidneys of BALB/c females treated with vancomycin (VA) for up to 400 mg/kg delivered intraperitoneally or intravenously. VA, an antibiotic treatment against methicillin-resistant Staphylococcus aureus, is nephrotoxic. Results provide insight into the molecular basis of VA nephrotoxicity.
Dieterich C, Puey A, Lin S, Swezey R et al. Gene expression analysis reveals new possible mechanisms of vancomycin-induced nephrotoxicity and identifies gene markers candidates. Toxicol Sci 2009 Jan;107(1):258-69. PMID: 18930951
