Analysis of Saccharomyces cerevisiae wild type cells grown under reduced oxygen tension. Heme synthesis requires oxygen, and yeast grown anaerobically exhibit an increased uptake of hemin. Results provide insight into the molecular mechanisms regulating heme uptake.
Protchenko O, Shakoury-Elizeh M, Keane P, Storey J et al. Role of PUG1 in inducible porphyrin and heme transport in Saccharomyces cerevisiae. Eukaryot Cell 2008 May;7(5):859-71. PMID: 18326586
