Analysis of brown adipose tissues from animals lacking KRAP. KRAP null mutants exhibit increased metabolic rate, reduced adiposity, improved glucose tolerance, hypoinsulinemia, and hypoleptinemia. Results provide insight into the molecular basis of the metabolic phenotype of KRAP deficient animals.
Fujimoto T, Miyasaka K, Koyanagi M, Tsunoda T et al. Altered energy homeostasis and resistance to diet-induced obesity in KRAP-deficient mice. PLoS One 2009;4(1):e4240. PMID: 19156225
