DataSet Record GDS3556: Expression Profiles Data Analysis Tools Sample Subsets
Title: Torcetrapib effect on adrenal carcinoma cell line
Cluster AnalysisGDS3556 Cluster Image
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Summary: Analysis of H295 adrenal carcinoma cells treated with torcetrapib, an anti-cholesterol drug. Adverse side effects of torcetrapib treatment include changes in blood pressure, potassium, sodium, and aldosterone. Results provide insight into the molecular basis of the off-target side effects.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
  • Hu X, Dietz JD, Xia C, Knight DR et al. Torcetrapib induces aldosterone and cortisol production by an intracellular calcium-mediated mechanism independently of cholesteryl ester transfer protein inhibition. Endocrinology 2009 May;150(5):2211-9. PMID: 19164467
Reference Series: GSE15918 Sample count: 9
Value type: transformed count Series published: 2009/05/02