In vitro pineal gland organ culture response to adrenergic/cAMP stimulation (Expt. C)
Summary:
Analysis of pineal organ cultures treated with norepinephrine (NE) and cAMP. Effects of forskolin also examined. Previous studies of night/day differentially expressed genes suggest control by NE/cAMP signaling. Results of this study expand the scope of the NE/cAMP regulatory cascade.
GPL1355:
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Citations:
Bailey MJ, Coon SL, Carter DA, Humphries A et al. Night/day changes in pineal expression of >600 genes: central role of adrenergic/cAMP signaling. J Biol Chem 2009 Mar 20;284(12):7606-22. PMID: 19103603
Davies JS, Klein DC, Carter DA. Selective genomic targeting by FRA-2/FOSL2 transcription factor: regulation of the Rgs4 gene is mediated by a variant activator protein 1 (AP-1) promoter sequence/CREB-binding protein (CBP) mechanism. J Biol Chem 2011 Apr 29;286(17):15227-39. PMID: 21367864
