Analysis of vastus lateralis muscle biopsies from insulin-sensitive subjects, insulin-resistant subjects, and diabetic patients, following insulin treatment. Results provide insight into the molecular basis of insulin action in skeletal muscle and the underlying defects causing insulin resistance.
GPL91:
[HG_U95A] Affymetrix Human Genome U95A Array
Citations:
Wu X, Wang J, Cui X, Maianu L et al. The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle. Endocrine 2007 Feb;31(1):5-17. PMID: 17709892
Wu X, Patki A, Lara-Castro C, Cui X et al. Genes and biochemical pathways in human skeletal muscle affecting resting energy expenditure and fuel partitioning. J Appl Physiol (1985) 2011 Mar;110(3):746-55. PMID: 21109598
