beta-TrCP inhibition and androgen ablation effects on prostate cancer cell line LAPC4
Summary:
Analysis of androgen-sensitive LAPC4 prostate cancer cells following beta-TrCP knockdown and androgen ablation. beta-TrCP inhibition reduces prostate cancer growth, showing an additive effect with androgen ablation. Results provide insight into the molecular basis of beta-TrCP inhibition.
GPL571:
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Citation:
Gluschnaider U, Hidas G, Cojocaru G, Yutkin V et al. beta-TrCP inhibition reduces prostate cancer cell growth via upregulation of the aryl hydrocarbon receptor. PLoS One 2010 Feb 5;5(2):e9060. PMID: 20140206
