Male and female genital imaginal discs during early morphogenesis: time course
Summary:
Analysis of female or male genital discs dissected during early morphogenesis (L3, P6, or P20). In flies, the sex-determination hierarchy terminates in the doublesex (dsx) gene. Results provide insight into molecular mechanisms downstream of dsx underlying sex-specific differentiation of genitalia.
Chatterjee SS, Uppendahl LD, Chowdhury MA, Ip PL et al. The female-specific doublesex isoform regulates pleiotropic transcription factors to pattern genital development in Drosophila. Development 2011 Mar;138(6):1099-109. PMID: 21343364