Analysis of optic nerve head and retina from 10.5-month-old, DBA/2J females at various stages of glaucoma. The DBA/2J strain is an inherited, later-onset, complex, and chronic model of glaucoma. Results provide insight into molecular mechanisms underlying the early stages of glaucoma.
Howell GR, Macalinao DG, Sousa GL, Walden M et al. Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma. J Clin Invest 2011 Apr;121(4):1429-44. PMID: 21383504
Howell GR, Walton DO, King BL, Libby RT et al. Datgan, a reusable software system for facile interrogation and visualization of complex transcription profiling data. BMC Genomics 2011 Aug 24;12:429. PMID: 21864367
