Image defocus effect on retina/retinal pigment epithelium: time course
Summary:
Analysis of retina and retinal pigment epithelium (RPE) from 1 week-old chicks wearing a unilateral spectacle lens of + or 15 diopters for 6 hours or 3 days. The spectacle lens induces refractive errors. Results provide insight into molecular mechanisms underlying refractive development.
Stone RA, McGlinn AM, Baldwin DA, Tobias JW et al. Image defocus and altered retinal gene expression in chick: clues to the pathogenesis of ametropia. Invest Ophthalmol Vis Sci 2011 Jul 29;52(8):5765-77. PMID: 21642623
