DataSet Record GDS3985: Expression Profiles Data Analysis Tools Sample Subsets
Title: TGF-beta/Smad3 signaling blockade effect on white adipose tissue
Cluster AnalysisGDS3985 Cluster Image
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Summary: Analysis of WAT from high fat diet-fed Smad3-/- mice and anti-TGF-beta antibody-treated, diet-induced obese (DIO) mice. Smad3 loss protects against DIO and diabetes. TGF-b signaling blockade protects against obesity and diabetes. Results provide insight into molecular mechanisms underlying diabetes.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citation:
  • Yadav H, Quijano C, Kamaraju AK, Gavrilova O et al. Protection from obesity and diabetes by blockade of TGF-β/Smad3 signaling. Cell Metab 2011 Jul 6;14(1):67-79. PMID: 21723505
Reference Series: GSE28598 Sample count: 12
Value type: transformed count Series published: 2011/07/13