DataSet Record GDS4018: Expression Profiles Data Analysis Tools Sample Subsets
Title: Anti-CD3 monoclonal antibody effect on splenic Foxp3+ regulatory T cells
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Summary: Analysis of sorted spleen T cells of BDC2.5 RAGo/o Foxp3 NOD mice after anti-CD3 treatment. Anti-CD3 treatment prevented diabetes development in BDC2.5.RAGo/o mice. Results provide insight into the mechanism of action of anti-CD3.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citation:
  • Nishio J, Feuerer M, Wong J, Mathis D et al. Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints. J Exp Med 2010 Aug 30;207(9):1879-89. PMID: 20679403
Reference Series: GSE22527 Sample count: 6
Value type: count Series published: 2010/06/23